Bibliography — Sophia Hober
81. |
Nilvebrant J, Alm T, Hober S†, & Löfblom J (2011) Engineering bispecificity into a single albumin-binding domain, PLoS ONE, In press
† Corresponding author |
80. |
Boström, T, Nilvebrant J & Sophia Hober (2011) Purification systems based of bacterial surface proteins, In Protein Purification, In press |
79. |
Hober S. (2011) Editorial: Biotech reviews – keeping upwith current developments, Biotechnology J, 6, 1031 |
78. |
Hjelm B, Brennan D, Zendehkrokh N, Eberhard, J, Nodin B, Gaber A, Pontén F, Johannesson H, Smaragdi K, Frantz C, Hober S, Johnson L, Påhlman S, Jirström K & Uhlén M, (2011) High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer, PROTEOMICS - Clinical Applications, In press |
77. |
Colwill K, Persson H, Jarvik NE, Wyrzucki A, Wojcik J, Koide A, Kossiakoff AA, Koide S, Sidhu S, Dyson MR, Pershad K, Pavlovic JD, Karatt-Vellatt A, Schofield DJ, Kay BK, McCafferty J, Mersmann M, Meier D, Mersmann J, Helmsing S, Hust M, Dübel S, Berkowicz S, Freemantle A, Spiegel M, Sawyer A, Layton D, Nice E, Dai A, Oliver Rocks O, Kelly Williton K, Frederic A, Fellouse FA, Hersi K, Pawson P, Nilsson P, Sundberg M, Sjöberg R, Sivertsson Å, Schwenk JM, Ottosson Takanen J, Hober S, Uhlén M, Dahlgren L, Flores A, Johansson I, Weigelt J, Crombet L, Loppnau P, Kozieradzki I, Cossar D, Arrowsmith CH, Edwards AM, Gräslund S (2011) A roadmap to generate renewable protein binders to the human proteome. NATURE METHODS. In press |
76. |
Ståhl PL, Bjursell MK, Mahdessian H, Hober S, Jirström K & Lundeberg J (2011) Translational database selection and multiplexed sequence capture for up front filtering of reliable breast cancer biomarker candidate, PLoS ONE, 6, e20794 |
75. |
Larsson K, Hofström C, Lindskog C, Hansson M, Angelidou P, Hökfelt T, Uhlén M, Wernérus H, Gräslund T, Hober S (2011) Novel antigen design for the generation of antibodies to G-protein-coupled receptors. Journal of immunological methods, 370, 14-23 |
74. |
Tegel H, Yderland L, Boström T, Eriksson C, Ukkonen K, Vasala A, Neubauer P, Jenny Ottosson J & Hober S (2011) Parallel production and verification of protein products using a novel high-throughput screening method, Biotechnology J, 6, 1018-1025 |
73. |
Gustavsson, E, Ek, S, Steen J, Kristensson M, Älgenäs C, Uhlén M, Wingren C, Ottosson J, Hober S & Borrebaeck C.A.K. (2011) Surrogate antigens as targets for proteome-wide binder selection, New Biotechnology, 28, 302-311 |
72. |
Falk R, Ramström M, Eriksson C, Uhlén M, Wernérus H & Hober S (2011) Targeted Protein Pullout From Human Tissue Samples Using Competitive Elution, Biotechnology J, 6, 28-37 |
71. |
Tegel H, Ottosson J & Hober S (2011) Enhancing the protein production levels in Escherichia coli with a strong promoter, FEBS J, 278, 729-739 |
70. |
Hober S. (2010) Editorial:
Global biotech challenges (2010) Biotechnology J, 5,
1249 |
69. |
Uhlen, M, Oksvold P, Fagerberg
L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf, C, Wester
K, Hober S, Wernerus H, Björling L & Ponten F
(2010) Towards a knowledge-based Human Protein Atlas, Nature
Biotech, 28, 1248-1250 |
68. |
Eriksson C, Schwenk JM, Sjöberg
A, Hober S (2010) Affibody molecule mediated depletion
of HSA and IgG using different buffer compositions – a 15
minute protocol for parallel processing of 1 - 48 samples.Biotechn
Appl Biochem, 56, 49-57 |
67. |
Alm T, Yderland L, Nilvebrant
J, Halldin, A & Hober S (2010) A small bispecific protein
selected for orthogonal affinity purification. Biotechnology
J, 5, 605-17 |
66. |
Pontén, F., Gry, M.,
Fagerberg, L., Lundberg, E., Asplund, A., Berglund, L., Oksvold,
P., Björling, E., Hober, S., Kampf, C., Navani, S., Nilsson,
P., Ottosson, J., Persson, A., Wernérus, H., Wester, K.
& Uhlén, M. (2010) A global view of protein
expression in human cells, tissues, and organs. Molecular
Systems Biology, 5, 337 |
65. |
Paavilainen L, Edvinsson
A, Asplund A, Hober S, Kampf C, Ponten F, et al. The impact
of tissue fixatives on morphology and antibody-based protein profiling
in tissues and cells (2009) J Histochem Cytochem, 58,
237-46. |
64. |
Hober, S. (2009) Editorial:
Biotech in the post genomic era. Biotechnology J, 4,
1631 |
63. |
Mulder, J, Björling,
E., Jonasson, K., Henrik Wernérus, H., Hober S., Hökfelt,
T & Uhlén M. (2009) Tissue profiling of the
mammalian central nervous system using human antibody-based proteomics.
Mol Cell Proteomics, 8, 1612-22 |
62. |
Steen, J., Ramström,
M., Uhlén, Hober, S., & Ottosson, J. (2009)
Automated sample preparation method for mass spectrometry analysis
on recombinant proteins. J.Chrom A, 20, 4457-4464 |
61. |
Larsson, K., Eriksson, C.,
Schwenk, J. M., Berglund, L., Wester, K., Uhlen, M., Hober, S.,
and Wernerus, H. (2009) Characterization of PrEST-based
antibodies towards human Cytokeratin-17. Journal of immunological
methods 342, 20-32. |
60. |
Tegel, H., Steen, J., Konrad,
A., Nikdin, H., Pettersson, K., Stenvall, M., Tourle, S., Wrethagen,
U., Xu, L., Yderland, L., Uhlen, M., Hober, S., and Ottosson,
J. (2009) High-throughput protein production--lessons from
scaling up from 10 to 288 recombinant proteins per week. Biotechnology
Journal 4, 5157. |
59. |
Rajangama, AS., Aspeborg,
H., Guerriero, G., Kumar, M., Arvestad, L., Pansri, P., Brown,
JCL., Hober, S., Blomqvist, K., Divne, C., Ezcurra, I., Sundberg,
B., Mellerowiczc, E. Bulone, V., & Teeri, T.T. (2008)
PttMAP20, a novel microtubule-associated protein in the secondary
cell walls of Populus tremula L x tremuloides
Michx, Plant Physiol, 148, 1283-1294 |
58. |
Berglund, L., Björling,
E., Oksvold, P., Fagerberg, L., Asplund, A., Al-Khalili Szigyarto,
C., Persson, A., Ottosson, J., Wernérus, H., Nilsson, P.,
Lundberg, E., Sivertsson, Å., Navani, S., Wester, K., Kampf,
C., Hober, S., Pontén, F. Uhlén, M. (2008)
A gene-centric human protein atlas for expression profiles based
on antibodies. Mol Cell Proteomics, 7, 2019-2027 |
57. |
Ramström, M., Zuberovic,
A., Grönwall, C., Hanrieder, J., Bergquist, J. & Hober,
S. (2008) Development of Affinity Columns for the Removal
of High-Abundant Proteins in Cerebrospinal Fluid, Biotechn
Appl Biochem, 52, 159-166 |
56. |
Paavilainen, L., Wernérus,
H., Nilsson, P. Uhlén, M., Hober, S., Wester, K & Pontén,
F (2008) Evaluation of mono-specific antibodies: A comparison
study with commercial analogues using immunohistochemistry on
tissue microarrays, Appl. Immunohistochem. & Molecular
Morphology, 16, 493-502 |
55. |
Uhlen, M. & Hober, S.,
(2008) Generation and validation of affinity reagents on a proteome-wide
level. J Mol Recognit, 22, 57-64 |
54. |
Hober, S & Uhlén,
M. (2007) Human Protein Atlas and the use of micro array
technologies, Curr. Op. Biotechn.19, 30-35 |
53. |
Bjorling E., Lindskog C.,
Oksvold P., Linne J., Kampf C., Hober S., Uhlen M. & Ponten
F. (2007) A web-based tool for in silico biomarker discovery
based on tissue-specific protein profiles in normal and cancer
tissues. Mol Cell Proteomics, 1535-9476 |
52. |
Grönwall, C., Sjöberg,
A., Ramström, M., Höide´n-Guthenberg, I., Hober,
S., Jonasson, P. & Ståhl, S. (2007) Affibody-mediated
transferrin depletion for proteomics applications, Biotechnology
J, 2, 1389-98 |
51. |
Hedhammar, M. & Hober,
S., (2007) Zbasic - A novel purification tag for efficient
protein recovery, J.Chrom A, 1161, 22–28 |
50. |
Alm T., Steen J., Ottosson
J. & Hober S. (2007) High-throughput protein purification
under denaturating conditions by the use of cation exchange chromatography,
Biotechnology J, 2, 709-716 |
49. |
Lerner, M, Corcoran, M.,
Nielsen, M.L., Zubarev, R., Pontén, F., Uhlén, M.,
Hober, S., Grandér, D. & Sangfelt, O. (2007)
The RBCC Gene RFP2 (Leu5) Encodes a Novel Transmembrane E3 Ubiquitin
Ligase Involved in ERAD, Mol Biol Cell. 18, 1670-1682 |
48. |
Mulder, J., Wernérus,
H., Shi, T.J., Pontén, F., Hober, S., Uhlén, M.
and Hökfelt, T. (2007) High throughput screening of
systematic generated antibodies against human gene products in
the rat nervous system. Neurosciences, 146, 1689-1703 |
| 47. |
Falk, R., Ramström,
M., Ståhl, S. & Hober, S. (2007) Approaches for
Systematic Proteome Exploration, Biomolecular Engineering,
24, 155-168 |
46. |
Hober, S., Nord, K., &
Linhult, M. (2007) Affinity chromatography for antibody
purification, J. Chrom B, 848, 40–47 |
45. |
Larsson, K., Wester, K.,
Nilsson, P., Uhlén, M., Hober, S., & Wernérus,
H. (2006) Multiplex immunization strategies for High-throughput
generation of monospecific antibodies for proteomic research,
J Immunol Methods, 315, 110-120 |
44. |
Persson, A., Hober, S. &
Uhlén, M. (2006) A human protein Atlas based on
Antibody Proteomics, Current Opinion in Molecular Therapeutics,
8, 185-190 |
43. |
Eriksson, C., Agaton, L.,
Ek, B., Kånge, R., Sundberg, M., Uhlén, M., Gustavsson,
M. & Hober, S. (2006) Microfluidic analysis of antibody
specificity in a compact disc format, J Proteome Research,
5, 1568-1574 |
42. |
Ek, S., Andréasson,
U., Hober, S., Kampf, C., Ponten, F., Uhlén, M., Merz,
H. & Borrebaeck, C.A.K (2006) From gene expression
analysis to tissue microarrays - a rational approach to identify
therapeutic and diagnostic targets in lymphoid malignancies Mol.
Cell. Proteomics, 6, 1072-1081 |
41. |
Hedhammar, M., Jung, H.R.
& Hober, S. (2006) Enzymatic cleavage of fusion proteins
using immobilised protease 3C, Prot. Ex. Purif. 47, 422-426 |
40. |
Steen, J., Uhlén,
M., Hober, S. & Ottosson, J. (2006) High throughput
protein purification using an automated set-up for high-yield
affinity chromatography, Prot. Ex. Purif. 46, 173-8 |
| 39. |
Hedhammar, M.,
Alm, T., Gräslund, T. & Hober, S. (2006) Single-step
recovery and solid phase refolding of inclusion body proteins
by the use of a polycationic purification tag. Biotechnology
J, 1, 187-196 |
| 38. |
Ahmadian, A., Ehn, M. &
Hober, S. (2006) Pyrosequencing: history, biochemistry
and future, CCA, 363, 83-94 |
| 37. |
Uhlén, M, Björling,
E., Agaton, C., Al-Khalili Szigyarto, C., Amini, B., Andersen,
E., Andersson, A.-C., Angelidou, P., Asplund, A., Asplund, C.,
Berglund, L., Bergström, K., Brumer, H., Cerjan, D., Ekström,
M., Elobeid, A., Eriksson, C., Fagerberg, L., Falk, R., Fall,
J., Forsberg, M., Björklund, M.G., Gumbel, K., Halimi, A.,
Hallin, I., Hamsten, C., Hansson, M., Hedhammar, M., Hercules.
G., Kampf, C., Larsson, K., Lindskog, M., Lodewyckx, W., Lund,
J., Lundeberg, J., Magnusson, K., Malm, E., Nilsson, P., Ödling,
J., Oksvold, P., Olsson, I., Öster, E., Ottosson, J., Paavilainen,
L., Persson, A., Rimini, R., Rockberg, J., Runeson, M., Sivertsson,
Å., SköllermoA., Steen, J., Stenvall, M., Sterky, F.,
Strömberg, S., Sundberg, M., Tegel, H., Tourle, S., Wahlund,
E., WaldénA., Wan, J., Wernérus, H., Westberg, J.,
Wester, K., Wrethagen, U., Xu, L.-L., Hober, S. & Pontén,
F., (2005) A human protein atlas for normal and cancer
tissues based on antibody proteomics, Mol. Cell. Proteomics,
4, 1920-1932 |
| 36. |
Hedhammar, M., Gräslund,
T., & Hober, S. (2005) Protein engineering strategies
for selective protein purification, CET, 28, 1315-1325 |
| 35. |
Stenvall, M., Steen, J.,
Uhlén, M., Hober, S. & Ottosson, J. (2005) High-throughput
solubility assay for purified recombinant protein immunogens,
BBA, 1752, 6-10 |
| 34. |
Nilsson, P., Paavilainen,
L., Larsson, K., Sundberg, M., Ödling, J., Andersson, AC.,
Kampf, C., Persson, A., Al-Khalili Szigyarto, C., Ottosson J.,
Björling, E., Hober, S., Wernerus, H., Wester K., Pontén,
F., & Uhlen M., (2005) Towards a human proteome atlas:
high-throughput generation of mono-specific antibodies (msAb)
for protein profiling using tissue microarrays. Proteomics,
17, 4327-4337 |
| 33. |
Hedhammar, M., Stenwall,
M., Lönneborg, R., Nord, O., Sjölin, O., Uhlén,
M., Ottosson, J., & Hober, S. (2005) Novel flow cytometry-based
method for analysis of expression levels in E coli giving information
about precipitated and soluble protein. J. Biotechn.
119, 133-46 |
| 32. |
Boström, M., Markland,
K., Sandén, AM, Hedhammar, M., Hober, S. & Larsson,
G. (2005) Effect of substrate feed rate on recombinant
protein secretion, degradation and inclusion body formation in
Escherichia coli. Appl. Microbiol. Biotechnol. 68, 82-90 |
| 31. |
Linhult, M, Gülich,
S & Hober, S. (2005) Affinity ligands for industrial
protein purification. Peptide and Protein Letters, In
press |
| 30. |
Hedhammar, M., Gräslund,
T. & Hober, S. (2004) A negatively charged purification
tag for selective anion-exchange recovery. PEDS, 17,
779-786 |
| 29. |
Agaton, C, Uhlén,
M. & Hober, S. (2004) Genome-based proteomics. Electrophoresis,
25, 1280-1288. |
| 28. |
Agaton, C., Falk, R., Höidén-Gutenberg,
I., Göstring, L., Uhlén, M. & Hober, S. (2004)
Controlled enrichment of monospecific polyclonal antibodies. J.Chrom
A, 1043, 33-40 |
27. |
Ehn M., Nourizad N., Bergström
K., Ahmadian A., Nyrén P., Lundeberg J. & Hober S.
(2004) Pyrosequencing on surface-attached genetic material by
use of DNA binding luciferase fusion proteins, Anal. Biochem.
329, 11-20. |
| 26. |
Linhult M., Gülich S.,
Gräslund T., Simon A., Sjöberg A., Nord K. & Hober
S. (2004) Improving the tolerance of a Protein A analogue
to repeated alkaline exposures§ using a by-pass mutagenesis
approach, Proteins, 55, 407-416 |
25. |
Linhult M., Gülich S.,
Gräslund T., Nygren P.-Å., & Hober S. (2003)
Evaluation of different linker regions for multimerization and
coupling chemistry for immobilization of a proteinaceous affinity
ligand, Protein Eng. 16, 1147-1152 |
| 24. |
Hober, S., Linhult, M.,
Gülich, S., Sjöberg, A., Nord, K., and Ståhl,
S. (2003) Stabilization of protein domains towards alkaline
conditions, In: V. Sedgwick (Ed.) Extended reports from the
2nd international symposium on downstream processing and genetically
engineered antibodies and related molecules. 32-34. |
| 23. |
Falk R., Agaton C, Kiesler
E., Shaobo J., Wieslander L., Visa N., Hober S & Ståhl
S. (2003) An improved dual expression concept generating
high-quality antibodies for proteomics research, Biotechn
Appl Biochem, 38, 231-239. |
| 22. |
Nourizad. K., Ehn, M., Gharizadeh,
B., Hober, S. & Nyrén, P. (2003) Expression
and purification of Apyrase A in Yeast, Prot. Ex. Purif.
27, 229-237 |
| 21. |
Ehn M., Ahmadian, A., Nilsson,
P., Lundeberg, J., Hober, S.(2002) Eschericha coli Single-Stranded
DNA-binding protein (SSB), a molecular tool for improved sequence
quality in pyrosequencing, Electrophoresis, 23, 3289-3299 |
| 20. |
Gülich, S., Linhult,
M., Ståhl, S., & Hober, S. (2002) Engineering
streptococcal protein G for increased alkaline stability, Protein
Eng. 15: 835-842 |
| 19. |
Gräslund, T., Hedhammar,
M., Uhlén, M., Nygren, P.-Å. & Hober, S.
(2002) Integrated strategy for selective expanded bed ion-exchange
adsorption and site-specific protein processing using gene fusion
technology, J. Biotechn., 96, 93-102 |
| 18. |
Johansson, M.U., Frick, I.-M,
Nilsson, H., Kraulis, P.J., Linhult, M., Hober, S., Jonasson,
P., NygrenP.-Å., Uhlén, M., Björck, L., Drakenberg,
T., Forsén, S., & Wikström, M. (2002) Structure,
specificity and mode of interaction for bacterial albumin-binding
modules, J. Biol. Chem. 277, 8114-8120 |
17. |
Ståhl, S., Hober, S.,
Nilsson, J., Uhlén, M. and Nygren, P.-Å. (2002)
Genetic approaches to facilitate purification. In Isolation
and purification of proteins (B. Mattiasson and R. Hatti-Kaul
Eds.) Marcel Dekker, New York |
16. |
Linhult, M, Binz, H. K, Uhlén,
M. & Hober, S. . (2002) Mutational analysis of the
interaction between Albumin Binding Domain from Streptococcal
protein G and Human Serum Albumin, Protein Science, 11,
206-213. |
15. |
Gräslund, T., Ehn, M.,
Lundin, G., Hedhammar, M., Uhlén, M. Nygren, P.-Å.
& Hober, S. (2002) Strategy for highly selective ion
exchange capture using a charge-polarizing fusion partner, J.
Chrom A, 942, 157-166. |
14. |
Hober, S., and Uhlén,
M. (2001) Design of affinityligands for purification of
biomolecules In: V. Sedgwick (Ed.) Extended reports from the
3rd international symposium on Expanded Bed Adsorbtion. 23-25. |
13. |
Hober, S., and Uhlén,
M. (2001) Design of affinityligands for purification of
biomolecules In: V. Sedgwick (Ed.) Extended reports from the
first international symposium on downstream processing and genetically
engineered antibodies and related molecules. 33-35. |
12. |
Ehn M., Nilsson, P., Uhlén,
M., Hober, S. (2001) Cloning, Overexpression, Rapid Isolation
and Biochemical Characterisation of Escherichia coli Single Stranded
DNA Binding Protein (SSB) Prot. Expr. Purif., 22,120-127 |
11. |
Gräslund, T., Lundin,
G., Uhlén, M., Nygren, P.-Å. & Hober, S.
(2000) Charge engineering of a protein domain to allow efficient
ion-exchange recovery. Protein Eng., 13, 703-709 |
10. |
Gülich, S., Linhult,
M., Uhlén, M., Nygren, P.-Å. & Hober, S.
(2000) Stability towards alkaline conditions can be engineered
into a protein ligand. J. Biotechn., 80, 169-178 |
9. |
Gülich S., Uhlén
M. & Hober, S. (2000) Protein engineering of an IgG-binding
domain allows milder elution conditions during affinity chromatography.
J. Biotechn., 76, 233-44. |
8. |
Hober S. & Uhlén,
M. (2000) Enhanced recovery and folding of recombinant
proteins using fusion protein strategies. In Protein engineering
in Industrial Biotechnology (L. Alberghina Eds.) Harwood
Academic Publishers gmbh, Amsterdam, p 23-39 |
7. |
Andersson, K., Gülich,
S., Hämäläinen, M. Nygren, P.-Å., Hober,
S. & Malmqvist, M. (1999) Kinetic characterization
of the interaction of the Z-fragment of protein A with mouse-IgG3
in a volume in chemical space. Proteins: Struct., Funct.,
Genet. 37, 494-498 |
6. |
Ståhl, S., Nilsson,
J., Hober, S., Uhlén, M. & Nygren, P.-Å.
(1999) Affinity fusions in biotechnology: focus on protein A and
protein G. In The Encyclopedia of Bioprocess Technology: Fermentation,
Biocatalysis and Bioseparation (M. C. Fleckinger and S. W.
Drew Ed) John Wiley and Sons Inc., New York, p 49-63 |
5. |
Hober, S., Lundström-Ljung,
J., Uhlén, M. & Nilsson, B. (1999) Insulin-like
Growth Factors I and II are Unable to Form and Maintain Their
Native Disulfides under in Vivo Redox Conditions. FEBS Letters
443: 271-276. |
4. |
Hober S., Uhlen M, Nilsson
B. (1997). Disulfide Exchange Folding of Disulfide Mutants
of Insulin-like Growth Factor I in vitro. Biochemistry
36: 4616-4622. |
| 3. |
Hober, S., Hansson, A.,
Uhlen, M., & Nilsson, B.(1994) Folding of Insulin-like
Growth Factor I Is Thermodynamically Controlled by Insulin-like
Growth Factor Binding Protein. Biochemistry 33, 6758-6761. |
2. |
Hober, S., Forsberg, G., Palm, G., Hartmanis, M.
& Nilsson, B. (1992) Disulfide Exchange Folding of Insulin-like
Growth Factor I. Biochemistry 31, 1749-1756 |
1. |
Strandberg, L., Hober, S.,
Uhlén, M. & Enfors, S.-O. (1990) Expression
and Characterization of a Tripartite Fusion Protein Consisting
of Chimeric IgG-binding Receptors and ß-galactosidase. J.
Biotechnol. 13, 83-96. |
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