Back: PN-JS-BA-MS-RS
Front: KD-MN-AG-AH-UI (May 2010) |
Research activities |
| Developing assays for proteomic protein
profiling of body fluids from clinical samples and biobank
collections by using affinity reagents on protein microarrays. |
| Microarray platforms |
• |
Suspension bead arrays |
• |
Planar microarrays |
| Antibody microarrays for |
| • |
directed biomarker discovery using disease
related selections of targets |
| • |
systematic biomarker discovery using undirected
selections of targets |
• |
protein profiling of clinical samples
such as plasma, serum and CSF |
• |
broad, multi-disease or single-disease
focused profiling |
| Antigen microarrays for |
• |
validation of all affinity
purified antibodies generated within the Human
Protein Atlas |
•
|
epitope mapping of antibodies
and affinity reagents |
• |
systematic screening of new
autoimmunogenic targets in body fluids |
| Reverse phase protein microarrays
for |
• |
simultaneous analysis of thousands
samples on selected targets |
• |
the protein profiling of body
fluids |
| Instrumental infrastructure
(examples) |
| Liquid Handling |
• |
Tecan Freedom Evo150 |
• |
Biotech EL406 |
• |
Thermo Scientific Matrix PlateMate |
• |
Qiagen Biorobot 8000 |
Suspension bead array |
• |
Luminex 200™ system |
• |
Luminex FLEXMAP 3D system |
| Biochip Array Printers |
• |
ArrayJet Marathon inkjet microarrayer |
• |
GeSim Nanoplotter 2.0E non-contact
microarrayer |
| Biochip Scanners |
• |
CapitalBio LuxScan HT 24 microarray
scanner |
• |
Agilent G2565BA 48 slide microarray
scanner |
| Funding (examples) |
• |
KTH |
• |
Science
for Life Laboratory |
• |
Pronova
VINN Excellence Centre for Protein Technology |
• |
Knut & Alice Wallenberg
Foundation |
• |
UCan |
• |
EU FP7 (BIO-NMD) |
