Contact details |
Per Berglund, Professor in Biochemistry
Short biography
2010-
Vice Dean of Faculty at KTH, see:
President's Group
2006-2010 Director of Undergrad. and Masters' studies at KTH Biotechnology
2009- Professor Biochemistry, KTH
2002-2009 Senior lecturer at
division of biochemistry, KTH
2000 Associate professor organic chemistry, KTH
1997-2001 Assistant professor at KTH Biotechnology
1995-96 Postdoc at Univ. of Toronto, Canada, with prof. J. Bryan Jones
1995 Ph.D. Organic Chemistry, Mid Sweden University, Sundsvall
Responsible for the annual course
Biocatalysis BB2460
Trends in Organic Chemistry - Enzymatic Synthesis Symposium,
KTH 2006
Kalle Hult's 65th Birthday Symposium,
KTH 2009 |
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Research |
Links to the research database at KTH:
Non-Natural Enzyme Reactions |
Enzymatic Synthesis |
BIO-AMINES |
Recent PhD and Lic theses:
Dr
Maria Svedendahl 2010 (12 MB pdf document)
Lic
Karim Cassimjee 2010 (1.2 MB pdf document)
Dr
Karim Cassimjee 2012 (1.2 MB pdf document) |
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Available student projects: see
list, Erasmus Exchange students are very welcome to
contact me |
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Current group and activities:
see this poster |
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Key Publications |
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●
Maria Svedendahl
Humble, Karim Engelmark Cassimjee, Vahak Abedi, Hans-Jürgen
Federsel and Per Berglund*. Key Amino Acid Residues for
Reversed or Improved Enantiospecificity of an
ω-Transaminase.
ChemCatChem 2012, in press.
doi:10.1002/cctc.201100487 |
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●
Maria S. Humble, Karim
E. Cassimjee, Maria Håkansson, Yengo R. Kimbung, Björn Walse, Vahak
Abedi, Hans-Jürgen Federsel, Per Berglund*, Derek T. Logan*. Crystal
structures of the Chromobacterium violaceum
w-transaminase
reveal major structural rearrangements upon binding of coenzyme PLP.
FEBS J. 2012, 279, 779-792.
doi:10.1111/j.1742-4658.2012.08468.x |
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●
Karim Engelmark
Cassimjee, Maria Svedendahl Humble, Valentina Miceli, Carla Granados
Colomina, Per Berglund.
Active
site quantification of an
ω-transaminase
by performing a half transamination reaction. ACS Catal.
2011, 1, 1051–1055.
DOI:
10.1021/cs200315h |
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● Maria Svedendahl Humble, Per Berglund.
Biocatalytic Promiscuity. Eur. J. Org. Chem. 2011, 2,
3391-3401. DOI:
10.1002/ejoc.201001664 |
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● Maria Svedendahl, Cecilia Branneby, Lina
Lindberg and Per Berglund. Reversed Enantiopreference of an
w-Transaminase by a
Single-Point Mutation. ChemCatChem 2010, 2,
976-980. http://dx.doi.org/10.1002/cctc.201000107 |
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● Karim Engelmark Cassimjee, Cecilia
Branneby, Vahak Abedi, Andrew Wells and Per Berglund.
Transaminations with isopropyl amine: equilibrium displacement with
yeast alcohol dehydrogenase coupled to in situ cofactor
regeneration. Chem. Commun. 2010, 46,
5569-5571.
http://dx.doi.org/10.1039/c0cc00050g |
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● Maria Svedendahl, Peter Carlqvist, Cecilia Branneby, Olof Allnér,
Anton Frise, Karl Hult, Per Berglund, Tore Brinck. Direct
Epoxidation in Candida antarctica lipase B Studied by Experiments
and Theory. ChemBioChem 2008, 9, 2443-2451.
http://dx.doi.org/10.1002/cbic.200800318 |
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● Karim Engelmark Cassimjee, Martin Trummer, Cecilia Branneby and Per
Berglund. Silica-Immobilized His6-tagged enzyme: Alanine racemase in
hydrophobic solvent. Biotechnol. Bioeng. 2008, 99,
712-716. http://dx.doi.org/10.1002/bit.21587 |
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● Karl Hult and Per Berglund. Enzyme promiscuity: mechanism and
applications. Trends Biotechnol. 2007, 25,
231-238. http://dx.doi.org/10.1016/j.tibtech.2007.03.002 |
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● Maria Svedendahl, Karl Hult, Per Berglund. Fast Carbon-Carbon Bond
Formation by a Promiscuous Lipase. J. Am. Chem. Soc. 2005,
127, 17988-17989.
http://dx.doi.org/10.1021/ja056660r |
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● Per Berglund, Seongsoon Park. Strategies for Altering Enzyme Reaction
Specificity for Applied Biocatalysis. Curr. Org. Chem. 2005,
9, 325-336. |
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● Peter Carlqvist, Maria Svedendahl, Cecilia Branneby, Karl Hult, Tore
Brinck, Per Berglund. Exploring the Active-Site of a Rationally
Redesigned Lipase for Catalysis of Michael-Type Additions. ChemBioChem
2005, 6, 331-336.
http://dx.doi.org/10.1002/cbic.200400213 |
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● Karl Hult and Per Berglund. Engineered Enzymes for Improved Organic
Synthesis. Curr. Opin. Biotechnol. 2003, 14,
395-400.
http://dx.doi.org/10.1016/S0958-1669(03)00095-8 |
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● Cecilia Branneby, Peter Carlqvist, Anders Magnusson, Karl Hult, Tore
Brinck, Per Berglund. Carbon-Carbon Bonds by Hydrolytic Enzymes. J.
Am. Chem. Soc. 2003, 125, 874-875.
http://dx.doi.org/10.1021/ja028056b |
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● Per Berglund. Controlling Lipase
Enantioselectivity for Organic Synthesis. Biomol. Eng.
2001, 18, 13-22.
http://dx.doi.org/10.1016/S1389-0344(01)00081-8 |
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